MEDICAL
NEWS, AN
UPDATE ON
%THE
NOVEL
CORONAVIRUS
OUTBREAK
%AND THE
STATUS
OF
WISCONSIN
%CASES.
%AS OF
TODAY,
THERE
REMAINS
JUST
%ONE
POSITIVE TEST
RESULT
IN
THE
%STATE.
%THAT
PERSON HAS BEEN
RECOVERING
%AT
HOME.
%14 OTHER
CASES
PENDING FOR
TEST
%OUTCOMES
HAVE
COME
BACK
%NEGATIVE.
%THIS
WEEK
UW-MADISON
ANNOUNCED
%SCIENTISTS
ON
CAMPUS WILL BE
AT
%THE
LEADING EDGE
OF
RESEARCH
TO%UNDERSTAND
THE
NEW
VIRUS.
%A
SAMPLE OF
THE
CORONAVIRUS
%BEING USED CAME
FROM
THE
U
W
%HOSPITAL WHERE
THE DANE
COUNTY
%PATIENT WHO
TESTED
POSITIVE
WAS
%SEEN.
%THOMAS
FRIEDRICH
IS A
PROFESSOR
%AT
THE
UW SCHOOL
OF
VETERINARIAN%MEDICINE.
%HE
JOINS
US
NOW
.
%THANKS
FOR
BEING
HERE.%>>
THANK
YOU
FOR
HAVING ME.
%>>
I
READ
AND
SEE
THAT
THE
%DISEASE IS
NOW
BEING
CALLED
%COVID-19.
%WHY IS
THAT?
%>>
SO
THE
VIRUS
NEEDS A
NAME.
%COVID-19
STANDS
FOR
CORONAVIRUS
%DISEASE,
2019.
%JUST A
FEW
DAYS
AGO,
THE
GLOBAL
%RESEARCH
COMMUNITY
DECIDED THAT
%THAT'S
THE
NAME WE
SHOULD CALL
%IT.%>>
I
THOUGHT IT WAS
MUCH
MORE
%SCIENTIFIC THAN
THAT.
%WHAT
IN
PARTICULAR ARE YOU
%LOOKING TO
FIND
OUT
ABOUT
THIS?
%>>
WEMENT
WE
WANT
TO
KNOW
WHY THESE
%SORT OF
EVENTS HAPPEN.
%ABOUT
75%
OF
MAJOR
HUMAN
%INFECTIOUS
DISEASES COME
%ORIGINALLY FROM
ANIMALS,
LIKE
%THIS
VIRUS
I
S
THOUGHT TO
DO,
BUT%THERE
ARE
MILLIONS
OF
VIRUSES
%AND
PARA
SITES
INFECTING
ANIMALS
%THAT
NEVER
BECOME
MAJOR
HUMAN
%DISEASES.
%SO WE
LIKE
TO
UNDERSTAND
HOW
IT
%CAME TO
BE.
%>>
AND WHAT IS
THE
END
GOAL
THEN
%OF
THAT
RESEARCH?
%>> SO
THE
END
GOAL
IS
TO
%UNDERSTAND
HOW
VIRUSES
EVOLVE
%AND THE
PATHWAYS THEY
NEED
TO
%TAKE TO GET
FROM
ANIMALS
TO
%HUMANS
AND
THEN
BECOME
SOMETHING
%THAT CAN
BE
TRANSMITTED
FROM
ONE
%HUMAN
TO
ANOTHER.
%THEY HAVE
TO
OVERCOME A
LOT
OF
%EVOLUTIONARY
BARRIERS TO
DO
THAT
%AND I
THINK
THAT
THE
MORE
%EXAMPLES WE HAVE
OF
PATHOGENS
%THAT
DO
THIS,
THE
BETTER WE
CAN
%DEFINE
WHAT
THOSE
BARRIERS
ARE
%AND
HOW
THEY
OVERCOME
THEM
AND
%THEN WE
CAN FIGURE OUT
HOPEFULLY
%HOW TO
STOP
THIS
FROM
HAPPENING.%>>
HOW
WELL-POISED
IS
U.S.
%MADISON
TO
REALLY
CRACK
THIS
%CASE
FOR
THE
REST OF
THE
WORLD
%ON
THIS
AND
OTHER
KIND
OF
%EMERGING
ILLNESSES?%>>
I
THINK
IT'S
IMPORTANT
TO
%
UNDERSCORE THAT THIS IS
TRULY A
%GLOBAL
EFFORT,
THAT THERE
ARE SO
%MANY
PIECES
TO
THE
PUZZLE
THAT
%NO ONE
TEAM
IS
LIKELY GOING TO
%BE
ABLE
TO
CRACK
THE
CASE
FOR
%EVERYONE.
%SO I
THINK
WE
ALL
ARE
TRYING TO
%CONTRIBUTE IN THE
WAY
THAT WE
%CAN.
%ONE OF
THE
MAIN
THINGS
THAT
THE
%GROUP
I'M
WORKING
WITH
IS
TRYING
%TO
DO
IS
GET
RESEARCHERS TO
BE
%MORE
OPEN
ABOUT
THE
DATA
THAT%THEY
ARE
GENERATING.
%SO
IN A
TIME
LIKE
THIS,
IT'S
%DIFFICULT
TO
KNOW
EVEN
THE
MOST
%BASIC THINGS
ABOUT
THE
BIOLOGY%OF
THE
NEW
VIRUS
AND
THE
%DECISIONS THAT
ARE
MADE
IN
%LABORATORIES AROUND THE WORLD
AS
%WE
START
TO
STUDY
THESE
VIRUSES
%WILL AFFECT HOW
WELL
AND
HOW
%QUICKLY WE CAN
HAVE
ANSWERS
TO
%IMPORTANT
QUESTIONS ABOUT HOW
%THE
VIRUS
GROWS
AND
WHAT
CELLS
%IT
INFECTS
AND
HOW
IT'S
%TRANSMITTED AND
SO
FORTH.
%AND
ONE OF
THE
MOST
IMPORTANT%THINGS I THINK IS
THAT
EARLY
ON
%THERE
MAY
BE
FAILURES
IN
%RESEARCH.
%SO
WE
MAY
TRY
SOMETHING
IN
OUR
%LAB
AND
IT
DOESN'T WORK.
%AND
THERE'S
REALLY
TRADITIONALLY
%NOT A
GOOD
MECHANISM
TO
%COMMUNICATE THAT
TO
THE
OUTSIDE
%WORLD.
%OR
IF
WE
FIND
SOMETHING
AND
I
T
%DOES
WORK,
THERE'S
NOT A
GOOD
%WAY TO
MAKE
THAT
INFORMATION
%AVAILABLE RAPIDLY.
%SO
WE'RE
TRYING
TO
SHARE
OUR
%DATA AS
QUICKLY AS
WE
GET
IT
SO
%OTHER
GROUPS AROUND THE
WORLD
%CAN
BUILD
ON
OUR
SUCCESSES OR
%LEARN
FROM
OUR
MISTAKES.%>> IS
IT
TRUE
THAT
OTHER
%RESEARCHERS,
SCIENTISTS ACROSS%THE
WORLD,
PERHAPS
AREN'T
BEING
%AS OPEN
AS
YOUR
TEAM
WOULD
LIKE%TO
SEE?
%>> I
THINK
THAT
PEOPLE ARE
%NATURALLY CAUTIOUS.
%SO,
NOW
RESEARCH
IS A
HUMAN
%ENTERPRISE AND
SOMETIMES
WE
MAKE
%MISTAKES.
%SOMETIMES WE
MAY
JUMP
TO
%CONCLUSIONS BASED
ON A
FEW
%INITIAL
FINDINGS
AND
THOSE
DON'T
%PAN
OUT.
%AND SO
I
THINK
PEOPLE
ARE
WARY,
%ESPECIALLY
IN A
VERY
POLITICALLY
%CHARGED
SITUATION WHERE
THERE'S%A
LOT
OF
CONCERN
AND
WORRY
THAT
%IF THEY
INTERPRET
THEIR
FIRST
%FEW
FINDINGS
INCORRECTLY,
THAT
%THAT
MAY
UNNECESSARILY WORRY
%SOMEONE.
%OR
THAT
IT
MAY
UNNECESSARILY
%CALM THINGS.
%AND
SO
I
UNDERSTAND THE
CONCERN.
%BUT I
THINK
THE
NEED
TO
RAPIDLY
%STAND
UP,
RESEARCH
ENTERPRISE
OF
%THIS
SIZE,
MAKES
IT
IMPORTANT
%THAT WE
ARE
TRANSPARENT.%>>
LRT
.
%WE NEED
TO
L